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. 2021 May 18;11:10546. doi: 10.1038/s41598-021-89948-0

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Chemical defensome genes in five model fish species. The genes were identified by searching gene names and using HMMER searches with Pfam profiles, followed by reciprocal or best-hit blast searches towards the zebrafish proteome. The gene families are organized in categories following Gene Ontology annotations and grouped by their role in the chemical defensome. The size of the disk represents the relative number of genes in the different fish genomes within each group, with the number of genes in a specific gene family as slices.