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. 2021 Apr 30;8:980–987. doi: 10.1016/j.toxrep.2021.04.014

Table 1.

Biological processes affected by Δ9-THC treatment. Upper and lower panels list biological processes that were up- and down-regulated, respectively.

Up-regulated
Biological process P-value
Ribosome biogenesis 1.04E-17
Response to endoplasmic reticulum stress 9.08E-07
Endoplasmic reticulum unfolded protein response 5.55E-07
Response to unfolded protein 4.51E-04
ER-associated ubiquitin-dependent protein catabolic process 8.94E-04



Down-regulated
Biological process P-value
Cardiac muscle contraction 7.00E-13
Muscle contraction 3.92E-10
Sarcomere organization 1.02E-08
Heart development 4.01E-08
Regulation of heart rate 6.65E-047
Regulation of heart rate by cardiac conduction 1.44E-06
Cardiac muscle tissue morphogenesis 1.48E-05