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. 2021 May 18;11(5):e399. doi: 10.1002/ctm2.399

FIGURE 2.

FIGURE 2

Homologous recombination deficiency (HRD) score was significantly correlated with the prognosis and molecular characteristics of TCGA‐OSC cohort. (A) Kaplan–Meier estimates of overall survival of patients with the HRD or non‐HRD tumors calculated by the HRD score in the TCGA‐OSC cohort. On the right are the AUC curves of HRD score in TCGA‐OSC cohort. (B) Violin plot of somatic mutations in the HRD and non‐HRD groups. Somatic mutation counts in the HRD group were significantly higher than those in the non‐HRD group (Wilcoxon signed rank test, ****< .0001). (C) Violin plot of fraction genome altered in the HRD and non‐HRD groups (Wilcoxon signed rank test, *< .05). (D) Two‐dimensional plan of fraction of the genome and somatic mutation counts in different subgroups (Kolmogorov–Simonov test, p < .01)