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. 2021 May 5;12:635076. doi: 10.3389/fimmu.2021.635076

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Copyright © 2021 Zhang, Zhang, Yu, Chen, Zhang, Wei, Zhang, Chen, Lin and Wu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Hyperforin ameliorates psoriatic symptoms and skin inflammation in IMQ-induced psoriatic mice. (A) Flow chart of this experiment. (B) The back-skin photos of mice were taken at 3th, 5th, 7th day after IMQ painting. (C) PASI scores in all groups of mice were evaluated daily and the statistical difference between all groups at 8th day was indicated. (D) H&E staining of the dorsal skin with the original magnification of 200×. Data are expressed as mean ± SD (n = 5 mice/group, *p < 0.05 vs. Model). One representative of three separate experiments is shown while all results were similar among these three experiments.