TABLE 3.

Treatment-related adverse events in all patients (n = 39).

	Any grade*	Grades 1–2*	Grade 3*
Adverse event	35 (90%)	31 (79%)	4 (11%)
Hypertension	12 (31%)	10 (26%)	2 (5%)
Diarrhea	6 (15%)	6 (15%)	–
Proteinuria	5 (13%)	5 (13%)	–
Rash	3 (8%)	2 (5%)	1 (3%)
Hand–foot syndrome	3 (8%)	3 (8%)	–
Hoarseness	2 (5%)	2 (5%)	–
Thrombocytopenia	2 (5%)	2 (5%)	–
Liver dysfunction	1 (3%)	1 (3%)	–
Decreased left ventricular ejection fraction	1 (3%)	–	1 (3%)

*Grading per the Common Terminology Criteria for Adverse Events, version 4.0.