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. 2021 May 18;12(6):504. doi: 10.1038/s41419-021-03792-8

Fig. 6. CaMKII mediates the TRPV1-promoted Nrf2 nuclear translocation in RAW264.7 cells.

Fig. 6

A Western blot and quantitative analyses of CaMKII and p-CaMKII protein levels in the cells treated with LPS with or without CPS for 5, 15, and 30 min. B Western blot analysis of cytosolic and nuclear Nrf2 protein levels in the cells treated with LPS and LPS + CPS with or without KN-93 for 3 h. C Immunofluorescence images and D quantitative analysis of Nrf2 in the cells treated with LPS and LPS + CPS with or without KN-93 for 3 h. Scale bars: 10 μm. Data (n = 3) are shown as mean ± SD. *P < 0.05; **P < 0.01; ***P < 0.001; NS nonsignificant.