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. 2021 May 18;11:10478. doi: 10.1038/s41598-021-90032-w

Table 2.

Top ten best performing models using all sequence and sequence-specific features sets ordered by ROC AUC.

All sequences Sequence-specific
Model Feature reduction ROC AUC mean (SD) Model Feature reduction Sequence ROC AUC mean (SD)
Lasso Full 0.953 (0.041) Lasso Full F 0.951 (0.049)
Enet Full 0.952 (0.038) Enet Full F 0.948 (0.049)
GBRM Full 0.940 (0.040) RF Full F 0.947 (0.042)
RF Full 0.937 (0.046) ada Full F 0.945 (0.038)
ada Full 0.933 (0.045) Lasso Full CE 0.943 (0.041)
Ridge Full 0.928 (0.053) GBRM Full F 0.943 (0.045)
GBRM Corr 0.925 (0.056) GBRM Lincomb F 0.943 (0.045)
SVMRad Full 0.921 (0.042) Lasso Full T1 0.941 (0.046)
RF Corr 0.920 (0.045) Enet Full T1 0.941 (0.041)
MLP Full 0.919 (0.055) GBRM Corr F 0.940 (0.046)

Enet: elastic net; Lasso (least absolute shrinkage and selection operator; GBRM: generalized boosted regression model; RF: random forest; ada: boosting of classification trees with adaBoost; SVMRad: SVM with a radial kernel; MLP: multi-layer perceptron; full: full feature set; corr: High correlation filter; lincomb: linear combinations filter; F: FLAIR; CE: T1-CE.