Table 3.
Predictive value of QTc interval for obstructive coronary artery disease by logistic regression model.
| CAD2 clinical model | ||||
|---|---|---|---|---|
| CAD2 + QTc (continuous) | CAD2 + QT prolongation | |||
| OR (95% CI) | p-value | OR (95% CI) | p-value | |
| Age (per 10 year) | 1.54 (1.38, 1.72) | < 0.001 | 1.55 (1.39, 1.73) | < 0.001 |
| Male | 1.84 (1.43, 2.38) | < 0.001 | 1.29 (0.997, 1.66) | 0.053 |
| Chest pain | ||||
| Non-specific | 1.00 | 1.00 | ||
| Atypical | 1.29 (0.90, 1.84) | 0.173 | 1.34 (0.93, 1.92) | 0.118 |
| Typical | 2.11 (1.46, 3.07) | < 0.001 | 2.20 (1.51, 3.20) | < 0.001 |
| DM | 1.79 (1.38, 2.33) | < 0.001 | 1.81 (1.39, 2.36) | < 0.001 |
| Hypertension | 1.18 (0.94, 1.49) | 0.157 | 1.18 (0.94, 1.49) | 0.152 |
| Dyslipidemia | 1.16 (0.89, 1.52) | 0.277 | 1.17 (0.89, 1.53) | 0.267 |
| Smoking | 1.81 (1.30, 2.50) | < 0.001 | 1.84 (1.33, 2.55) | < 0.001 |
| QTc (continuous) | 1.14 (1.09, 1.18) | < 0.001 | ||
| QT prolongation | 2.27 (1.81, 2.85) | < 0.001 | ||
| UDF model | ||||
|---|---|---|---|---|
| UDF + QTc (continuous) | UDF + QT prolongation | |||
| OR (95% CI) | p-value | OR (95% CI) | p-value | |
| Age (per 10 year) | 1.59 (1.43, 1.76) | < 0.001 | 1.60 (1.44, 1.77) | < 0.001 |
| Male | 2.20 (1.73, 2.79) | < 0.001 | 1.51 (1.19, 1.92) | 0.006 |
| Chest pain | ||||
| Non-specific | 1.00 | 1.00 | ||
| Atypical | 1.27 (0.89, 1.82) | 0.182 | 1.32 (0.92, 1.89) | 0.128 |
| Typical | 2.14 (1.52, 3.01) | < 0.001 | 2.21 (1.57, 3.12) | < 0.001 |
| QTc (continuous) | 1.14 (1.10, 1.19) | < 0.001 | ||
| QT prolongation | 2.34 (1.87, 2.93) | < 0.001 | ||
CAD2 CAD Consortium clinical score, UDF updated Diamond-Forrester score, OR odds ratio, CI confidence interval, QTc corrected QT, DM diabetes mellitus.