Figure 6.
Increased pericyte loss hallmarks iron-loaded Leprdb/dbmice. A-B) Analysis of pericyte (A) and endothelial cell (B) number, normalized against the capillary area, in the eyes of 15-week old mice with the genotype and the gender indicated. C-D) Characterization of pericyte (C) and endothelial cells (D) in the eyes of 30-week old male mice. E) Representative histological analysis of the microvasculature of the retina in 30-week-old male mice with the genotype indicated. All data are reported as mean ± SEM. Six or more mice per group were analyzed. Student's t-test p-value: ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001; ∗∗∗∗p < 0.0001.