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. 2021 May 5;9:558285. doi: 10.3389/fcell.2021.558285

TABLE 4.

Comparison of cross-section and flexural strength in animals with and without alendronate treatment between the femurs on the fractured and non-fractured side.

Age Alendronate Cross-section (mm2)–fracture Mean ± SD Cross-section (mm2) no fracture Mean ± SD P Value Flexural strength (MPa)–fracture Mean ± SD Flexural strength (MPa) no fracture Mean ± SD P Value
Middle-age No (O) 51.70 ± 22.37 20.30 ± 2.32 0.002 4.21 ± 2.87 80.43 ± 33.49 <0.001
Yes (OA) 55.35 ± 28.78 19.89 ± 4.01 0.006 13.67 ± 16.42 72.25 ± 18.03 <0.001
Young No (Y) 25.45 ± 4.33 12.87 ± 2.01 0.008 24.50 ± 9.95 112.09 ± 0.25 0.002
Yes (YA) 37.40 ± 17.34 16.68 ± 1.89 0.022 27.37 ± 23.45 83,64 ± 25.10 0.006

Paired T Test, with significance level 0.05.