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. 2021 May 5;11:673506. doi: 10.3389/fonc.2021.673506

Figure 1.

Figure 1

Morphological aspect of a B cell precursor leukemia (SEM) and a T-ALL (Jurkat) cell lines. TEM images of: (A) SEM cells at 8000 magnification; (B) Jurkat cells at 8000 magnification. n: nucleolus, he: heterochromatin, m: mitochondria. Scale bars correspond to 2 μm. For TEM analysis, samples were fixed in 2.5% glutaraldehyde and post-fixed in 2% osmium tetroxide, dehydrated in acetone solutions and included in Araldite Durcupan ACM (Fluka). Samples were then counterstained with uranyl acetate in saturated solution and lead citrate and observed under transmission electron microscope Zeiss EM910 at 100 Kv.