TABLE 1.
Top 10 correlated gene pairs changed to the opposite direction from the yellow and medium orchid modules between normal and LUAD samples.
| Molecule X | Molecule Y | r1 (normal) | r2 (tumor) | lfdra (difference) | Module color |
| HIGD1B | DUOX1 | –0.58 | 0.53 | 0 | Yellow |
| FAM162B | DUOX1 | –0.56 | 0.51 | 0 | Yellow |
| EPCAM | CAV1 | 0.65 | –0.40 | 0 | Yellow |
| FAM162B | DUOXA1 | –0.59 | 0.46 | 4.67E-12 | Yellow |
| PHACTR1 | HIGD1B | –0.58 | 0.45 | 1.47E-11 | Yellow |
| DUOX1 | COX4I2 | –0.55 | 0.47 | 3.16E-11 | Yellow |
| IL33 | DUOX1 | –0.53 | 0.48 | 8.28E-11 | Yellow |
| FXYD1 | ATP13A4-AS1 | –0.58 | 0.41 | 1.29E-10 | Yellow |
| MMP19 | CASS4 | –0.43 | 0.55 | 2.30E-10 | Yellow |
| ATP13A4-AS1 | AGER | –0.40 | 0.58 | 2.51E-10 | Yellow |
| VPS72 | PIP5K1A | –0.47 | 0.73 | 0 | Mediumorchid |
| VPS45 | PIP5K1A | –0.41 | 0.69 | 0 | Mediumorchid |
| UBE2Q1 | ILF2 | –0.60 | 0.58 | 0 | Mediumorchid |
| TARS2 | PIP5K1A | –0.54 | 0.66 | 0 | Mediumorchid |
| TARS2 | ENSA | –0.46 | 0.62 | 0 | Mediumorchid |
| PYGO2 | PIP5K1A | –0.59 | 0.62 | 0 | Mediumorchid |
| PSMD4 | PIP5K1A | –0.55 | 0.60 | 0 | Mediumorchid |
| PRUNE | PIP5K1A | –0.58 | 0.70 | 0 | Mediumorchid |
| PRUNE | CDC42SE1 | –0.55 | 0.59 | 0 | Mediumorchid |
| PIP5K1A | LYSMD1 | –0.74 | 0.71 | 0 | Mediumorchid |
aLocal FDR.