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. 2021 May 5;11:638598. doi: 10.3389/fcimb.2021.638598

Table 2.

The FICI of each combination of different antibiotics with DLP4.

S. hyicus ACCC 61734
Combination Variety MICa (μg/ml) MICc (μg/ml) FIC FICI
DLP4-CRO DLP4 4 1 0.25 0.3125a
CRO 4 0.25 0.0625
DLP4-AMX DLP4 4 0.5 0.125 0.375a
AMX 1 0.25 0.25
DLP4-PEN DLP4 4 1 0.25 0.3125a
PEN 1 0.0625 0.0625
DLP4-OFX DLP4 4 0.5 0.125 0.625b
OFX 16 8 0.5

MICa indicates the MIC of drug used alone; MICc indicates the MIC of drug used in combination;

aSynergic effect; bAdditive effect.