Table 3.

Results of single-label classifiers on target diseases detection.

a. Performance (AUC) on IBS
Testing set	SD		MD
Training set	SD	MD	SD	MD
RF	0.681 ± 0.039	0.661 ± 0.032	0.718 ± 0.025	0.757 ± 0.018
GBDT	0.713 ± 0.025	0.689 ± 0.036	0.731 ± 0.022	0.787 ± 0.015

b. Performance (AUC) on Lung disease
Testing set	SD		MD
Training set	SD	MD	SD	MD
RF	0.671 ±0.28	0.538 ±0.023	0.618 ±0.024	0.727 ±0.025
GBDT	0.659 ±0.017	0.571 ±0.021	0.614 ±0.006	0.754 ±0.019

c. Performance (AUC) on Migraine
Testing set	SD		MD
Training set	SD	MD	SD	MD
RF	0.686 ±0.018	0.619 ± 0.021	0.670 ± 0.021	0.749 ± 0.017
GBDT	0.682 ± 0.019	0.642 ± 0.015	0.656 ± 0.018	0.764 ± 0.017

d. Performance (AUC) on Thyroid
Testing set	SD		MD
Training set	SD	MD	SD	MD
RF	0.714 ± 0.021	0.683 ± 0.017	0.755 ± 0.032	0.769 ± 0.032
GBDT	0.728 ± 0.026	0.700 ± 0.025	0.764 ± 0.024	0.794 ± 0.024

e. Performance (AUC) on Autoimmune
Testing set	SD		MD
Training set	SD	MD	SD	MD
RF	0.664 ± 0.05	0.650 ± 0.036	0.715 ± 0.039	0.776 ± 0.035
GBDT	0.689 ± 0.041	0.665 ± 0.031	0.741 ± 0.022	0.790 ± 0.041