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Evolutionary trend of the neural probe shape and material from very stiff needle‐like shaft to soft material‐based mesh/neuron‐like structures. A) Stiff shank or needle‐like neural probe, B) neural probe with thick fiber and polymer substrate, C) stretchable probe with serpentine metallic structures, D) ultrathin substrate‐based probe, E) ultra‐thin polymer‐based probe with soft conductive material, and F) mesh‐based probe.
