Table 2.

Comparison of MADRS scores and plasma VEGF levels between responders and nonresponders and between remitters and nonremitters in patients with unipolar and bipolar depression using linear mixed model analysis.

Variables	Group-by-time interaction		Time main effect		Group main effect
	F	p	F	p	F	p
MADRS scores	62.25	<0.001	230.63	<0.001	56.13	<0.001
Plasma VEGF levels (ng/ml)	4.89	0.010	4.78	0.011	1.58	0.211

Bolded values are p < 0.05.

MADRS, the Montgomery–Åsberg Depression Rating Scale; VEGF, vascular endothelial growth factor.