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. Author manuscript; available in PMC: 2021 May 19.
Published in final edited form as: Methods Mol Biol. 2019;1982:191–229. doi: 10.1007/978-1-4939-9424-3_12

Table 1.

Human NOX variants, accession numbers, and main characteristics

NOX isoform Variant number (V) and NCBI accession # Notes about the variant (see accession # for full details)
NOX1 (V1) NM_007052.4
(V2) NM_013955.2
(V3) NM-001271815		 Full length
Deletion of 1503–1610 (exon 10)
Deletion of 459–543 (exon 4)
NOX2 (CYBB) NM_000397.3 Full length
NOX3 NM_015718.2 Full length
NOX4 (V1) NM_016931.4
(V2) NM_001143836.2
(V3) NM_001143837
(V4) NM_001291926
(V5) NM_001291927.1
(V6) NM_001291929.1
(V7) NR_120406.1
(V8) NM_001300995.1 		Full length
Deletion of 1546–1656 (exon 14)
Deletion of 1–375 (exon 1)
Deletion of 472–475 (part of exon 3)
Deletion of 1–375 (exon 1)
Deletion of 1–471 (exon 1 and 2)
Non-coding
Deletion of 1–375 (exon 1) and of nucleotides corresponding to exon 14 of full length
NOX5 [8, 9] (α) NM_001184779.1
(β) NR_033672.1
(γ) NM_024505.3 (δ) NR_033671.2
(ε) AF317889
(ζ) NM_001184780.1 		NOX5α; 18 aa extension at the start of the N-terminus (exon 3); deletion of 27 aa in exon 6; predominant isoform in spleen
NOX5β; deletion of 27 aa in exon 6; predominant isoform in testis
NOX5γ complete exon 6 without the 18 aa extension of the N-terminus
NOX5δ complete exon 6 with the 18 aa extension of the N-terminus
NOX5ε (a.k.a. NOX5-S); truncated from exon 3 through most of exon 7
NOX5ζ: contains an extra 25 aa at the start of the N-terminus
DUOX1 NM_017434.4 Full length
DUOX2 NM_014080.4 Full length