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. Author manuscript; available in PMC: 2021 May 19.
Published in final edited form as: Cancer Lett. 2018 Oct 10;440-441:82–93. doi: 10.1016/j.canlet.2018.10.007

Fig. 6. Selonsertib inhibited the efflux function of ABCB1 and ABCG2 transporters.

Fig. 6.

The effect of selonsertib on efflux of [3H]-paclitaxel in KB-3–1 and KB-C2 (A, B) and SW620 and SW620/Ad300 (C, D) cells. The effect of selonsertib on efflux of [3H]-mitoxantrone in NCI-H460 and NCI-H460/MX20 (E, F) and S1 and S1-M1–80 (G, H) cells. Data are mean ± SD, representative of three independent experiments. *p < 0.05, compared with control group. Selo, selonsertib; Vera, verapamil and Ko, Ko 143.