. Author manuscript; available in PMC: 2021 Dec 15.

Published in final edited form as: J Acquir Immune Defic Syndr. 2020 Dec 15;85(5):651–658. doi: 10.1097/QAI.0000000000002502

Table 3.

Comparison of methotrexate exposure in this study and published literature. Data represent Geometric mean (90% CIs)

Dose (mg)	Administration Route	C_max (ng/mL)	Reference
10	PO	144 (127, 164)	This study
7.5	PO	217 (180, 254)	Sinnett et al²⁶
10	IM	233 (207, 259)	Combe et al²³
10	IM	268 (237, 299)	Anaya et al²⁴
10	IM	350 (253, 446)	Edelman et al²⁵