Table 1.
Baseline Characteristics of Study Participants with First Ischemic Stroke and Age- and Sex-Matched Controls
| Control Subjects (n= 2463) | First Ischemic Stroke (n= 2463) | P value | |
|---|---|---|---|
| Age, yrs | 67.6 ± 9.4 | 67.6 ± 9.4 | 0.998 |
| Male, no. (%) | 1110 (45.1) | 1110 (45.1) | 1.000 |
| SBP, mmHg | 147.7 ± 20.8 | 153.1 ± 21.9 | <0.001 |
| DBP, mmHg | 86.7 ± 13.1 | 90.0 ± 13.7 | <0.001 |
| BMI, kg/m2 | 25.5 ± 3.7 | 26.0 ± 4.0 | <0.001 |
| Fasting glucose, mg/dL | 6.0 ± 2.0 | 6.5 ± 2.5 | <0.001 |
| History of diabetes, yes, no. (%) | 222 (9.0) | 363 (14.7) | <0.001 |
| TC, mg/dL | 212.8 ± 46.5 | 213.2 ± 47.4 | 0.751 |
| TG, mg/dL | 129.0 ± 86.2 | 143.7 ± 96.0 | <0.001 |
| HDL-C, mg/dL | 62.0 ± 15.6 | 59.6 ± 15.1 | <0.001 |
| LDL-C, mg/dL | 126.1 ± 32.4 | 128.7 ± 32.7 | 0.004 |
| Total homocysteine, μmol/L | 13.5 ± 8.8 | 14.1 ± 7.8 | 0.009 |
| ≥15μmol/L, no. (%) | 558 (22.7) | 675 (27.4) | <0.001 |
| Smoking status, no. (%) | 0.051 | ||
| Never | 1786 (72.5) | 1754 (71.2) | |
| Former | 196 (8.0) | 168 (6.8) | |
| Current | 481 (19.5) | 541 (22.0) | |
| Alcohol consumption, no. (%) | 0.001 | ||
| Never | 1785 (72.5) | 1849 (75.1) | |
| Former | 89 (3.6) | 120 (4.9) | |
| Current | 589 (23.9) | 492 (20.0) | |
| Antihypertensive drugs, yes, no. (%) | 906 (36.8) | 1193 (48.4) | <0.001 |
| Glucose lowering drugs, yes, no. (%) | 105 (4.3) | 198 (8.0) | <0.001 |
| eGFR, mL/min per 1.73 m2 | 95.0 ± 13.8 | 93.9 ± 14.6 | 0.007 |