Table 3.
Combined Association of HDL-C and LDL-C Tertiles with First IS
| HDL-C Tertiles mg/dL | LDL-C Tertiles mg/dL | N (%) | Crude OR (95% CI) | Adjusted OR* (95% CI) | P-value |
|---|---|---|---|---|---|
| T1 (≥65.4) | <111.4 | 180 (40.8) | Ref | Ref | |
| 111.4 −138.1 | 236 (45.8) | 1.22 (0.94,1.58) | 1.10 (0.84,1.45) | 0.483 | |
| ≥138.1 | 328 (47.9) | 1.32 (1.03,1.69) | 1.10 (0.85,1.43) | 0.479 | |
| T2 (53.0–65.4) | <111.4 | 228 (46.5) | 1.26 (0.97,1.64) | 1.12 (0.85,1.47) | 0.425 |
| 111.4 −138.1 | 302 (49.7) | 1.45 (1.13,1.86) | 1.21 (0.92,1.57) | 0.169 | |
| ≥138.1 | 316 (53.8) | 1.69 (1.31,2.17) | 1.27 (0.97,1.67) | 0.088 | |
| T3 (<53.0) | <111.4 | 361 (50.4) | 1.45 (1.14,1.85) | 1.16 (0.89,1.51) | 0.278 |
| 111.4 −138.1 | 289 (54.5) | 1.75 (1.35,2.27) | 1.25 (0.94,1.67) | 0.123 | |
| ≥138.1 | 223 (63.0) | 2.47 (1.85,3.30) | 1.66 (1.19,2.31) | 0.003 |
Notes: *Adjusted for body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting glucose, smoking status, alcohol consumption, use of antihypertensive drugs, and glucose-lowering drugs, total homocysteine (tHcy), and estimated glomerular filtration rate (eGFR), and TG (continuous).