Fig. 2.

Properties of the acetylation and succinylation proteome. (A, B) Heat maps showing features of the flanking sequences for all Lys acetylation and succinylation sites, respectively. Multiple hypothesis tests were performed for the p-values. (C) Venn diagram showing the overlapped results between significant Lys acetylation and succinylation sites in hippocampal tissue from gut microbiota-dysbiosis mice. (D) Venn diagram showing the overlapped results between significant acetylated and succinylated proteins in hippocampal tissue from gut microbiota-dysbiosis mice. (E) Secondary structure distribution and surface accessibility prediction of significantly acetylated sites. (F) Secondary structure distribution and surface accessibility prediction of significantly succinylated sites.