Table 3.
Demographic characteristics of control subject and patients with RIF in mid-secretory phase recruited in this study.
| Variable | Control (n = 18) | RIF (n = 20) | P |
|---|---|---|---|
| Age (y) | 30.56 ± 3.45 | 30.50 ± 3.25 | 0.960 |
| BMI (kg/m2) | 22.88 ± 3.52 | 21.63 ± 2.34 | 0.215 |
| Basal FSH level (mIU/mL) | 6.08 ± 1.35 | 6.85 ± 1.87 | 0.164 |
| Basal LH level (mIU/mL) | 4.19 ± 2.29 | 3.56 ± 2.16 | 0.946 |
| Basal E2 level (pg/mL) | 37.99 ± 13.56 | 40.50 ± 18.99 | 0.646 |
| P4 level on the day of ET (ng/mL) * | 13.27 ± 6.72 | 16.61 ± 5.20 | 0.055 |
| P4 level on the day of endometrial biopsy (ng/mL) | 15.40 ± 4.17 | 17.21 ± 3.14 | 0.137 |
| Endometrial thickness on the day of embryo transfer (mm) | 8.67 ± 0.39 | 8.47 ± 0.38 | 0.125 |
| Median embryo-transfer number (range) | 1 (1, 1) | 4 (3, 10) | < 0.001a |
| Number of embryos per transfer (%) | 0.909b | ||
| 1 | 6/18 (33.3%) | 31/97 (32.0%) | |
| 2 | 12/18 (66.7%) | 66/97 (68.0%) | |
| Median score of transferred day-3 embryos (range) | 8 (7, 9) | 8 (7, 10) | 0.564a |
| Score of transferred blastocysts (%) | – | ||
| 3BB | (/, /) | 11/58 (19.0%) | |
| 4AB | (/, /) | 25/58 (41.3%) | |
| 4BB | (/, /) | 22/58 (37.9%) |
The data are presented as the mean ± SD and were analyzed by Student’s t-test, unless otherwise stated. *P4 levels on the day of ET > 40 ng/ml in the control (5 for the fresh embryo-transfer cycle and 2 for the frozen embryo-transfer cycle) and RIF (5 for the fresh embryo-transfer cycle and 8 for the frozen embryo-transfer cycle) groups were excluded. BMI, body–mass index; LH, luteinizing hormone; FSH, follicle-stimulating hormone; E2, estradiol; P4, progesterone. a, Mann–Whitney test; b, Fisher’s exact test