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CYP51A-related azole resistance mechanisms. The named hot spots are based on the names suggested by Dudakova et al. (ref). ITC, itraconazole; PSC, posaconazole; VRC, voriconazole; Pan-R, pan-azole resistance; ITC-R, resistance to itraconazole alone; ITC-PSC-R, cross itraconazole-posaconazole resistance; VRC-R, voriconazole resistance. *L98H was described to be either alone or together with other substitutions
