Table 2.

Primary outcome of maternal OGTT plasma glucose values at 28 (24–32) weeks gestation

OGTT time point	Control		Intervention		β (95% CI) for loge glucose (loge mmol/L)
	n	Plasma glucose (mmol/L)	n	Plasma glucose (mmol/L)	Adjusted*	Fully adjusted†
Fasting	290	4.41 (4.08–4.63)	295	4.30 (4.08–4.63)	−0.004 (−0.018 to 0.011)	0.0002 (−0.014 to 0.014)
P value		—		0.55	0.63	0.98
1 h	283	8.02 (6.60–9.23)	294	8.24 (6.93–9.45)	0.025 (−0.014 to 0.064)	0.036 (−0.003 to 0.074)
P value		—		0.26	0.22	0.07
2 h	287	6.49 (5.51–7.70)	295	6.60 (5.84–8.02)	0.040 (0.004–0.077)	0.043 (0.006–0.081)
P value		—		0.03	0.03	0.02

Data are median (interquartile range [unadjusted]) unless otherwise indicated. All P values (t tests on log_e-transformed glucose and linear regressions) were not significant ≥0.017 (a priori statistical significance is P < 0.017).

^*Log_e glucose at 24–32 weeks adjusted for site, ethnicity, and baseline log_e glucose (for fasting and 2 h only; baseline 1-h glucose not available); n = 584 and 578 for fasting and 2-h glucose, respectively, as a result of missing values for corresponding preconception glucose.

^†Log_e glucose at 24–32 weeks adjusted for site, ethnicity, maternal age, prepregnancy BMI, preconception smoking, parity, family history of diabetes, and baseline log_e glucose (for fasting and 2 h only; baseline 1-h glucose not available); n = 581, 574, and 575 for fasting, 1-h, and 2-h glucose, respectively, as a result of missing data.