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. 2020 May 10;44(5):1108–1115. doi: 10.2337/dc20-0307

Table 3.

Sensitivity analyses modeling cost-effectiveness of interventions

Sensitivity analysis scenario EUC CHW only CHW + PL CHW + PL vs. CHW only CHW only vs. EUC CHW + PL vs. EUC
18-month intervention with persistent intervention benefits
 Total cost1 ($)
   10 years 70,851 70,878 69,985 –893 27 –866
   20 years 124,401 124,265 122,467 –1,798 –135 –1,933
   30 years 159,312 159,367 157,491 –1,876 54 –1,822
 QALE (QALYs)
   10 years 4.48 4.49 4.51 0.0234 0.0051 0.0286
   20 years 7.14 7.16 7.23 0.0714 0.0206 0.0919
   30 years 8.58 8.61 8.73 0.1183 0.0348 0.1532
 Cost per QALY gained ($)
   10 years Cost saving 5,148 Cost saving
   20 years Cost saving Cost saving Cost saving
   30 years Cost saving 1,570 Cost saving
Ongoing intervention with persistent intervention benefits
 Total cost2 ($)
   10 years 70,851 71,252 70,545 –706 400 –306
   20 years 124,401 124,867 123,371 –1,497 467 –1,029
   30 years 159,312 160,109 158,604 –1,505 796 –709
 QALE (QALYs)
   10 years 4.48 4.49 4.51 0.0234 0.0051 0.0286
   20 years 7.14 7.16 7.23 0.0714 0.0206 0.0919
   30 years 8.58 8.61 8.73 0.1183 0.0348 0.1532
 Cost per QALY gained ($)
   10 years Cost saving 78,148 Cost saving
   20 years Cost saving 22,719 Cost saving
   30 years Cost saving 22,862 Cost saving
1

Total cost was a combination of the intervention cost and outcome cost. The intervention cost was $234, $820, and $1,599 per participant for the EUC, CHW-only, and CHW + PL interventions, respectively, over the 18-month intervention period of the REACH Detroit trial. The outcome cost derived from the direct medical costs of diabetes and its complications was estimated by the MMD.

2

Total cost was a combination of the intervention cost and outcome cost. The intervention cost was $234, $820, and $1,599 per participant for the EUC, CHW-only, and CHW + PL interventions, respectively, over the 18-month intervention period of the REACH Detroit trial. The ongoing intervention cost per participant per year was $43.80 and $65.70 for the CHW-only and CHW + PL interventions over the simulation period, respectively, assuming that a total of 2 h per participant per year was made by the CHW or PL to make contact with the participants. The ongoing cost would support the ongoing CHW-only and CHW + PL interventions to maintain the trial-observed intervention effects over the simulation time horizon. The outcome cost derived from the direct medical costs of diabetes and its complications was estimated by the MMD.