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. 2020 May 10;44(5):1151–1158. doi: 10.2337/dc20-1710

Table 2.

Crude and sequentially adjusted HRs for each 1% increase in glycosylated hemoglobin (A1C) and the risk for adjudicated cardiovascular events* during follow-up among participants with and without diabetes

Model** Without diabetes With diabetes
Crude (unadjusted) 1.12 (0.94, 1.33) 1.20 (1.07, 1.35)
+ Demographic 1.10 (0.91, 1.33) 1.23 (1.09, 1.39)
+ CV risk factors 0.97 (0.79, 1.19) 1.23 (1.08, 1.39)
+ SES (income/education) 0.95 (0.77, 1.17) 1.21 (1.07, 1.38)
+ Residential segregation indices 0.94 (0.76, 1.16) 1.23 (1.08, 1.40)
*

Cardiovascular events are defined as stroke, nonfatal MI, or CHD death.

**

Demographics include sex, race, age, and race–age interaction; CV risk factors include BMI, smoking status, systolic and diastolic BP, LDL and HDL, and logarithm of CRP; socioeconomic status (SES) includes income level and education level; and residential segregation indices include tertiles of dissimilarity index, isolation index, and interaction index.