Table 2.
Multivariable logistic regression models of severe NAFLD on the risk of subclinical atherosclerosis in terms of CAC ≧ 100, CAC ≧ 400, CAD-RADS ≧ 3, and presences of vulnerable plaque(s)
| Model 1 (CAC score ≧ 100) | Model 2 (CAC score ≧ 400) | Model 3 (CAD-RADS ≧ 3) | Model 4 (vulnerable plaque) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OR | CI | p value | OR | CI | p value | OR | CI | p value | OR | CI | p value | |
| Framingham risk score (%) | 1.072 | 1.038–1.106 | < 0.0001 | 1.096 | 1.041–1.154 | < 0.0001 | 1.071 | 1.032–1.110 | < 0.0001 | 1.079 | 1.050–1.108 | < 0.0001 |
| Body-fat percentage | 1.005 | 0.968–1.043 | 0.789 | 1.016 | 0.970–1.064 | 0.504 | 1.011 | 0.976–1.048 | 0.537 | 0.981 | 0.943–1.020 | 0.330 |
| Severe NAFLD* | 2.946 | 1.017–8.530 | 0.046 | 4.402 | 1.149–16.862 | 0.031 | 4.091 | 1.396–11.993 | 0.010 | 2.906 | 1.107–7.624 | 0.030 |
OR odds ratio, CI confidence interval, NAFLD Non-alcoholic fatty liver disease, CAC coronary artery calcium, CAD-RADS the coronary artery disease-reporting and data system
*Reference group normal, mild and moderate NAFLD groups (severe NAFLD vs. reference group)