Table 2.
Demographic features of cases presenting with PIMS-TS, with illness onset after 1st March 2020.
| Total with any PIMS | PIMS-TS only | PIMS-TS/KD | PIMS-TS/TSS | PIMS-TS/ KD/ TSS | |
|---|---|---|---|---|---|
| n (%) | n (%) | n (%) | n (%) | n (%) | |
| Total | 268 (100·0%) | 216 (100·0%) | 13 (100·0%) | 28 (100·0%) | 11 (100·0%) |
| Sex | |||||
| Male | 161 (60·1%) | 124 (57·4%) | 11 (84·6%) | 21 (75·0%) | 5 (45·5%) |
| Female | 90 (33·6%) | 79 (36·6%) | 2 (15·4%) | 5 (17·9%) | 4 (36·4%) |
| Age group | |||||
| <1 year | 23 (8·6%) | 19 (8·8%) | 2 (15·4%) | 2 (7·1%) | 0 (0·0%) |
| 1–4 years | 65 (24·3%) | 54 (25·0%) | 4 (30·8%) | 4 (14·3%) | 3 (27·3%) |
| 5–9 years | 80 (29·9%) | 61 (28·2%) | 4 (30·8%) | 10 (35·7%) | 5 (45·5%) |
| 10–15 years | 100 (37·3%) | 82 (38·0%) | 3 (23·1%) | 12 (42·9%) | 3 (27·3%) |
| Median age (IQR) | 8·21 years (4·03–12·09) | 7·84 years (4·03–12·60) | 5·19 years (1·85–9·75) | 8·83 years (6·15–12·32) | 7·09 years (4·32–10·07) |
| Weight 2 SDs above mean for age/sex | 36 (13·4%) | 32 (14·8%) | 0 (0·0%) | 1 (3·6%) | 3 (27·3%) |
| Underlying medical conditions | |||||
| Any | 51 (19·0%) | 43 (19·9%) | 2 (15·4%) | 2 (7·1%) | 4 (36·4%) |
| Neurodevelopmental | 12 (4·5%) | 10 (4·6%) | 2 (15·4%) | 0 (0·0%) | 0 (0·0%) |
| Gastrointestinal | 7 (2·6%) | 6 (2·8%) | 0 (0·0%) | 0 (0·0%) | 1 (9·1%) |
| Haematological | 7 (2·6%) | 4 (1·9%) | 0 (0·0%) | 0 (0·0%) | 3 (27·3%) |
| Asthma requiring regular medication | 6 (2·2%) | 6 (2·8%) | 0 (0·0%) | 0 (0·0%) | 0 (0·0%) |
| Ethnicity | |||||
| White | 114 (42·5%) | 105 (48·6%) | 2 (15·4%) | 4 (14·3%) | 3 (27·3%) |
| Black/ African/ Caribbean/ Black British | 60 (22·4%) | 42 (19·4%) | 3 (23·1%) | 10 (35·7%) | 5 (45·5%) |
| Asian/ Asian British | 63 (23·5%) | 44 (20·4%) | 6 (46·2%) | 12 (42·9%) | 1 (9·1%) |
| Mixed/ multiple ethnic groups | 11 (4·1%) | 9 (4·2%) | 1 (7·7%) | 0 (0·0%) | 1 (9·1%) |
| Other ethnic groups | 10 (3·7%) | 8 (3·7%) | 0 (0·0%) | 1 (3·6%) | 1 (9·1%) |
| Outcome | |||||
| Admitted to PICU | 118 (44·0%) | 89 (41·2%) | 4 (30·8%) | 19 (67·9%) | 6 (54·5%) |
| Required conventional ventilation/ High Frequency Oscillation | 44 (16·4%) | 28 (13·0%) | 1 (7·7%) | 10 (35·7%) | 5 (45·5%) |
| Required peritoneal dialysis | 1 (0·4%) | 1 (0·5%) | 0 (0·0%) | 0 (0·0%) | 0 (0·0%) |
| Required inotropes | 80 (29·9%) | 56 (25·9%) | 3 (23·1%) | 15 (53·6%) | 6 (54·5%) |
| Died | 3 (1·1%) | 2 (0·9%) | 0 (0·0%) | 1 (3·6%) | 0 (0·0%) |
| Median duration of hospital stay (IQR) | 8 days (5–11) |
7 days (5–10) |
5 days (4–6) |
13 days (10·5–17) |
9 days (5–12) |
| Median duration of PICU stay (IQR) | 3 days (2–7) |
3 days (2–6) |
2·5 days (1·5–3·5) |
6 days (2–8) |
3·5 days (2–5) |
IQR Interquartile Range; n Number of cases; PICU Paediatric Intensive Care Unit; SD Standard Deviation.