Cytokine correlations with changes in movement-matched slow wave activity. (a) Scatterplot of the change in movement-matched SWA from baseline to peak LPS vs log IL-6 concentration. Markers represent values for individual animals. The line indicates the polynomial least-squares fit (using the MATLAB function ‘regress’) for LPS-only groups, and the shading indicates the 95% prediction interval of the regression line. The r2 value for the fit is also indicated. (b) Scatterplot of the change in movement-matched SWA from baseline to peak vs log MCP-1 concentration. IL-6, interleukin-6; LPS, lipopolysaccharide; MCP-1, monocyte chemoattractant protein-1; PXM, piroxicam; SWA, slow wave activity; VEH, vehicle.