EEG and movement time course summary across groups. (a) The time series of SWA (2–4 Hz) normalised to mean spectral power (2–80 Hz) are shown for all LPS groups (vehicle, low LPS, and high LPS are the same as in Fig. 2). Symbols represent the mean percent change in SWA from baseline across all animals at each LPS dose at each recording hour. Error bars represent plus or minus standard error of the mean. (b) Gamma power time series. (c) Alpha wPLI time series. (d) Movement time series. Bars indicate plus or minus standard error of the mean. CAF, caffeine citrate; LPS, lipopolysaccharide; PXM, piroxicam; SWA, slow wave activity; VEH, vehicle; wPLI, weighted phase lag index.