Fig. 9. (a) Chemical structure of BCN-TPET-TEG and schematic illustration of bio-orthogonal labeling-mediated light-up of BCN-TPET-TEG on the cell membrane. (b) Confocal images of 4T1 cells after BCN-TPET-TEG (5 μg mL−1) bio-orthogonal labeling; CellMask Green is used for the colocalization test. (c) Fluorescence images of DBCO-Cy5 or BCN-TPET-TEG treated 4T1-bearing mice with/without AzAcSA pretreatment. Reproduced from ref. 65 with permission. Copyright 2018 Wiley-VCH.
