IC₅₀ of chloroquine–triazole (38), thiosemicarbazide (39 and 40), and –piperidine (41) hybrids.

Compound	IC50 (nM) ± SD CQR	IC50 (nM) ± SD CQS
38(a–c)	2.94–75.01	38.75–40.00
39(a–e)	0.10–0.36 μg ml−1	—
40(a–k)	0.02–0.26 μg mL−1	—
41(a–e)	25 ± 8.9–69 ± 11.3	12 ± 1.0–236 ± 32