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. 2021 May 19;41(8):1783–1796. doi: 10.1038/s41372-021-01083-w

Table 1.

Comparison of systemic corticosteroids [4, 7, 14, 16].

Drug Approximate equivalent dose (mg)a Glucocorticoid potency Mineralocorticoid potency Duration of action (h)
Hydrocortisone 20 1 1

Short acting

8–12

Prednisone

Prednisolone

5 4 0.8

Intermediate acting

12–36

Methylprednisolone 4 5 0.5

Intermediate acting

12–36

Dexamethasone 0.75 25 0

Long acting

>36

Betamethasone 0.75 25 0

Long acting

>36

Fludrocortisone b 10 125

Intermediate acting

12–36

aDose equivalents are reported for oral/IV administration; alternate routes may vary and are not presented here.

bFludrocortisone is used for mineralocorticoid activity only.