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. 2021 May 14;100(19):e25707. doi: 10.1097/MD.0000000000025707

Table 2.

The demographic data, clinical and biochemical parameters in quartiles of thyroid stimulation hormone.

TSH tertile 1 TSH tertile 2 TSH tertile 3 TSH tertile 4 P
Male
 n 6169 5820 6073 6345
 Age (yr) 42.3 ± 8.6234 41.3 ± 8.31 41.2 ± 8.21 41.4 ± 8.21 <.001
 Body mass index (kg/m2) 24.0 ± 2.84 24.0 ± 2.9 24.2 ± 3.0 24.2 ± 3.01 <.001
 Systolic blood pressure (mm Hg) 118.1 ± 14.04 118.3 ± 13.74 118.7 ± 13.5 119.6 ± 13.712 <.001
 Diastolic blood pressure (mm Hg) 74.8 ± 10.234 75.3 ± 10.14 75.7 ± 10.114 76.6 ± 10.2123 <.001
 HDL-C (mg/dl) 1.088 ± 0.323 1.093 ± 0.319 1.079 ± 0.323 1.081 ± 0.320 .055
 LDL-C (mg/dl) 3.387 ± 0.859 3.420 ± 0.853 3.421 ± 0.856 3.431 ± 0.868 .025
 TG (mg/dL) 1.520 ± 0.85434 1.549 ± 0.8574 1.595 ± 0.90014 1.677 ± 0.948123 <.001
 TSH (U/_mL) 0.682 ± 0.190234 1.105 ± 0.100134 1.503 ± 0.142124 2.448 ± 0.665123 <.001
 FPIS (μU/min) 188.6 ± 170.134 188.7 ± 174.234 205.4 ± 239.612 206.1 ± 223.312 <.001
 SPIS (pmol/mmol) 0.079 ± 0.0494 0.081 ± 0.057 0.084 ± 0.068 0.084 ± 0.0821 <.001
 IR (10−4 · min−1 · pmol−1 · L−1) 3.697 ± 0.02434 3.699 ± 0.0244 3.700 ± 0.02614 3.702 ± 0.026123 <.001
 GE (10−2 · dL · min−1 · kg−1) 0.017 ± 0.0034 0.017 ± 0.0034 0.017 ± 0.0034 0.017 ± 0.003123 <.001
Female
 n 6274 6233 6262 6120
 Age (yr) 43.5 ± 9.023 42.5 ± 8.51 42.4 ± 8.51 42.9 ± 8.5 <.001
 Body mass index (kg/m2) 23.1 ± 3.1 23.0 ± 3.14 23.0 ± 3.24 23.3 ± 3.323 <.001
 Systolic blood pressure (mm Hg) 114.9 ± 15.4 114.2 ± 15.14 114.7 ± 15.3 115.7 ± 15.42 <.001
 Diastolic blood pressure (mmHg) 71.9 ± 10.24 72.0 ± 14.14 72.3 ± 13.1 73.1 ± 10.412 <.001
 HDL-C (mg/dl) 1.306 ± 0.3504 1.297 ± 0.342 1.306 ± 0.3474 1.281 ± 0.34313 <.001
 LDL-C (mg/dl) 3.251 ± 0.827 3.258 ± 0.814 3.284 ± 0.831 3.291 ± 0.848 .018
 TG (mg/dL) 1.128 ± 0.6384 1.125 ± 0.6294 1.162 ± 0.6624 1.230 ± 0.711123 <.001
 TSH (U/_mL) 0.656 ± 0.226234 1.163 ± 0.126134 1.651 ± 0.172124 2.809 ± 0.763123 <.001
 FPIS (μU/min) 131.1 ± 150.64 133.4 ± 163.64 136.3 ± 179.6 146.9 ± 190.912 <.001
 SPIS (pmol/mmol) 0.072 ± 0.073 0.072 ± 0.073 0.073 ± 0.062 0.076 ± 0.070 .002
 IR (10−4 · min−1 · pmol−1 · L−1) 3.687 ± 0.0234 3.687 ± 0.0244 3.688 ± 0.0254 3.691 ± 0.025123 <.001
 GE (10−2 · dL · min−1 · kg−1) 0.018 ± 0.0034 0.019 ± 0.0024 0.019 ± 0.0024 0.018 ± 0.003123 <.001

FPIS = first phase insulin secretion, GE = glucose effectiveness, HDL-C = high-density lipoprotein cholesterol, IR = insulin resistance, LDL-C = low-density lipoprotein cholesterol, SPIS = second phase insulin secretion, TG = triglyceride, TSH = thyroid stimulating hormone.

Data are shown mean ± SD, the upper case of the numbers on the left side of the values indicate there are significant difference against that particular group