Table 2.
The demographic data, clinical and biochemical parameters in quartiles of thyroid stimulation hormone.
TSH tertile 1 | TSH tertile 2 | TSH tertile 3 | TSH tertile 4 | P | |
Male | |||||
n | 6169 | 5820 | 6073 | 6345 | |
Age (yr) | 42.3 ± 8.6234 | 41.3 ± 8.31 | 41.2 ± 8.21 | 41.4 ± 8.21 | <.001 |
Body mass index (kg/m2) | 24.0 ± 2.84 | 24.0 ± 2.9 | 24.2 ± 3.0 | 24.2 ± 3.01 | <.001 |
Systolic blood pressure (mm Hg) | 118.1 ± 14.04 | 118.3 ± 13.74 | 118.7 ± 13.5 | 119.6 ± 13.712 | <.001 |
Diastolic blood pressure (mm Hg) | 74.8 ± 10.234 | 75.3 ± 10.14 | 75.7 ± 10.114 | 76.6 ± 10.2123 | <.001 |
HDL-C (mg/dl) | 1.088 ± 0.323 | 1.093 ± 0.319 | 1.079 ± 0.323 | 1.081 ± 0.320 | .055 |
LDL-C (mg/dl) | 3.387 ± 0.859 | 3.420 ± 0.853 | 3.421 ± 0.856 | 3.431 ± 0.868 | .025 |
TG (mg/dL) | 1.520 ± 0.85434 | 1.549 ± 0.8574 | 1.595 ± 0.90014 | 1.677 ± 0.948123 | <.001 |
TSH (U/_mL) | 0.682 ± 0.190234 | 1.105 ± 0.100134 | 1.503 ± 0.142124 | 2.448 ± 0.665123 | <.001 |
FPIS (μU/min) | 188.6 ± 170.134 | 188.7 ± 174.234 | 205.4 ± 239.612 | 206.1 ± 223.312 | <.001 |
SPIS (pmol/mmol) | 0.079 ± 0.0494 | 0.081 ± 0.057 | 0.084 ± 0.068 | 0.084 ± 0.0821 | <.001 |
IR (10−4 · min−1 · pmol−1 · L−1) | 3.697 ± 0.02434 | 3.699 ± 0.0244 | 3.700 ± 0.02614 | 3.702 ± 0.026123 | <.001 |
GE (10−2 · dL · min−1 · kg−1) | 0.017 ± 0.0034 | 0.017 ± 0.0034 | 0.017 ± 0.0034 | 0.017 ± 0.003123 | <.001 |
Female | |||||
n | 6274 | 6233 | 6262 | 6120 | |
Age (yr) | 43.5 ± 9.023 | 42.5 ± 8.51 | 42.4 ± 8.51 | 42.9 ± 8.5 | <.001 |
Body mass index (kg/m2) | 23.1 ± 3.1 | 23.0 ± 3.14 | 23.0 ± 3.24 | 23.3 ± 3.323 | <.001 |
Systolic blood pressure (mm Hg) | 114.9 ± 15.4 | 114.2 ± 15.14 | 114.7 ± 15.3 | 115.7 ± 15.42 | <.001 |
Diastolic blood pressure (mmHg) | 71.9 ± 10.24 | 72.0 ± 14.14 | 72.3 ± 13.1 | 73.1 ± 10.412 | <.001 |
HDL-C (mg/dl) | 1.306 ± 0.3504 | 1.297 ± 0.342 | 1.306 ± 0.3474 | 1.281 ± 0.34313 | <.001 |
LDL-C (mg/dl) | 3.251 ± 0.827 | 3.258 ± 0.814 | 3.284 ± 0.831 | 3.291 ± 0.848 | .018 |
TG (mg/dL) | 1.128 ± 0.6384 | 1.125 ± 0.6294 | 1.162 ± 0.6624 | 1.230 ± 0.711123 | <.001 |
TSH (U/_mL) | 0.656 ± 0.226234 | 1.163 ± 0.126134 | 1.651 ± 0.172124 | 2.809 ± 0.763123 | <.001 |
FPIS (μU/min) | 131.1 ± 150.64 | 133.4 ± 163.64 | 136.3 ± 179.6 | 146.9 ± 190.912 | <.001 |
SPIS (pmol/mmol) | 0.072 ± 0.073 | 0.072 ± 0.073 | 0.073 ± 0.062 | 0.076 ± 0.070 | .002 |
IR (10−4 · min−1 · pmol−1 · L−1) | 3.687 ± 0.0234 | 3.687 ± 0.0244 | 3.688 ± 0.0254 | 3.691 ± 0.025123 | <.001 |
GE (10−2 · dL · min−1 · kg−1) | 0.018 ± 0.0034 | 0.019 ± 0.0024 | 0.019 ± 0.0024 | 0.018 ± 0.003123 | <.001 |
FPIS = first phase insulin secretion, GE = glucose effectiveness, HDL-C = high-density lipoprotein cholesterol, IR = insulin resistance, LDL-C = low-density lipoprotein cholesterol, SPIS = second phase insulin secretion, TG = triglyceride, TSH = thyroid stimulating hormone.
Data are shown mean ± SD, the upper case of the numbers on the left side of the values indicate there are significant difference against that particular group