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. 2021 May 14;3(5):e0398. doi: 10.1097/CCE.0000000000000398

TABLE 1.

Characteristics of Included Studies

Reference Country Total No.of Participants Population Type of Balanced Crystalloid Compared Cumulative Volume of Fluid, Mean (sd) or [Range]
Ramanathan et al (16) United States 68 Pregnant women undergoing cesarean section Ringer’s Lactate vs Plasmalyte A 1,200 mL; 1,200 mL
Ratcliffe et al (17) United Kingdom 29 Pediatric heart surgery patients Plasmalyte vs Hartmann’s 380 mL (222.6); 413 mL (220)
Attalla et al (18) Egypt 30 Cholecystectomy patients Ringer’s Lactate vs Ringer’s Acetate 846.67 mL (109.33); 836.67 mL (106.01)
Shimada et al (19) Japan 20 Elective aortic aneurysm repair patients Ringer’s Acetate vs Ringer’s Bicarbonate 4,061 mL (871); 4,480 mL (857)
Hadimioglu et al (20) Turkey 90 Kidney transplant recipients Plasmalyte vs Ringer’s Lactate 2,756 mL (800); 2,770 mL (820)
Galas et al (21) Brazil 40 Septic shock patients Ringer’s Lactate vs Ringerfundin Not reported
Zadák et al (22) Czech Republic 14 Healthy volunteers Plasmalyte vs Ringerfundin 2,000 mL; 2,000 mL
Shin et al (23) South Korea 104 Live liver donor patients Plasmalyte vs Ringer’s Lactate 3,302 mL (575); 3,407 mL (715)
Hasman et al (24) Turkey 90 Dehydrated emergency department patients Plasmalyte vs Ringer’s Lactate 20 mL/kg/hr × 2 hr
Kiss et al (25) Hungary 102 Pregnant women undergoing cesarean section Ringer’s Lactate vs balanced Ringers 572 mL (442); 617 mL (260)
Vichitvejpaisal et al (26) Thailand 90 Endoscopy outpatients Ringer’s Lactate vs Ringer’s Acetate 1,140 mL (169); 1,046 mL (167)
Scotti et al (27) Italy 20 Cardiac bypass patients Ringer’s Lactate vs novel solution 10 ± 5 mL/kg
Weinberg et al (28) Australia 60 Liver resection patients Plasmalyte vs Hartman’s 2,000 mL [1,425–3,000]; 3,000 mL [1,800–4,000]
Benoit et al (29) Belgium 204 Adult ICU patients Plasmalyte vs Sterofundin 1,000 mL; 1,000 mL
Kumar et al (30) India 80 Adult surgical patients Ringer’s Lactate vs Sterofundin vs Plasmalyte vs Kabilyte Not reported
Rajan et al (31) India 60 Major head and neck surgery patients Ringer’s Lactate vs Sterofundin 5,116.7 mL (1,744); 5,646.7 mL (1,295.0)
Uvizl et al (32) Czech Republic 112 Postop ICU patients Plasmalyte vs Ringerfundin 1,000 mL; 1,000 mL
Omar and Mathivha (33) South Africa 86 Adult ICU patients Bicarbonate-balanced fluida vs conventional balanced fluidb Not reported
Rawat et al (34) India 49 Adult ICU patients Ringer’s Lactate vs Acetate 20 mL/kg/hr × 1 hr, 10 mL/kg/hr × 1 hr
Weinberg et al (35) Australia 50 Cardiac surgery patients Plasmalyte vs Hartman’s 2,000 mL; 2,000 mL
Pfortmueller et al (36) Switzerland 148 Cardiac surgery patients Ringer’s Lactate vs Ringer’s Acetate 6,104 mL [4,769–7,855]; 6,677 mL [5,325–8,479]
Chaussard et al (37) France 28 Burn patients in ICU Plasmalyte vs Ringer’s Lactate 15,680 mL; 19,626 mL
Joseph et al (38) India 40 Pediatric surgery patients Ringer’s Lactate vs Sterofundin Not reported
King et al (39) United States 59 Adolescent spinal surgery patients Ringer’s Lactate vs Normosol-R 48 mL/kg (87); 35 mL/kg (23)

aNa 143 mmol/L, Cl 99 mmol/L, Hco3 49 mmol/L.

bNa 130 mmol/L, Cl 110 mmol/L, Hco3 <27 mmol/L.