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. 2021 May 14;100(19):e25913. doi: 10.1097/MD.0000000000025913

Table 3.

Symptomatic, laboratory, and radiological characteristics of clinical classifications in the COVID-19 patients.

N Mild Common Severe Critical t2 P
N 157 2 110 30 15
Age 51.49 ± 17.39 26.00 ± 1.41 46.60 ± 15.56 62.70 ± 15.82 68.27 ± 10.85 17.217 .000
Gender 5.724 .017
 Male 81 (51.6%) 0 (0.0%) 53 (48.2%) 16 (53.3%) 12 (80.0%)
 Female 76 (48.4%) 2 (100.0%) 57 (51.8%) 14 (46.7%) 3 (20.0%)
Signs and symptoms
 Fever 118 (75.2%) 1 (50.0%) 76 (69.1%) 26 (86.7%) 15 (100.0%) 9.814 .002
 Cough 94 (59.9%) 0 (0.0%) 68 (61.8%) 17 (56.7%) 9 (60.0%) 0.004 .947
 Fatigue 39 (24.8%) 0 (0.0%) 24 (21.8%) 9 (30.0%) 6 (40.0%) 3.277 .070
 Chest tightness&dyspnea 28 (17.8%) 0 (0.0%) 11 (10.0%) 10 (33.3%) 7 (46.7%) 17.918 .000
 Sore throat 13 (8.3%) 0 (0.0%) 10 (9.1%) 3 (10.0%) 0 (0.0%) 0.602 .438
 Headache 6 (3.8%) 0 (0.0%) 6 (5.5%) 0 (0.0%) 0 (0.0%) 1.882 .170
Muscle soreness 22 (14.0%) 0 (0.0%) 14 (12.7%) 8 (26.7%) 0 (0.0%) 0.002 .965
Nausea or vomiting 7 (4.5%) 0 (0.0%) 5 (4.5%) 1 (3.3%) 1 (6.7%) 0.057 .812
 Diarrhea 16 (10.2%) 0 (0.0%) 15 (13.6%) 1 (3.3%) 0 (0.0%) 3.710 .054
 Anorexia 28 (17.8%) 0 (0.0%) 19 (17.3%) 6 (20.0%) 3 (20.0%) 0.264 .608
SpO2 92.5 ± 15.0 98.5 ± 0.70 96.7 ± 2.4 92.4 ± 6.0 60.7 ± 33.8 49.588 .000
CT 17.958 .000
Ground-glass opacity 30 (19.4) 0 (0.0%) 26 (23.6%) 2 (6.7%) 2 (13.3%)
Local patchy shadowing 15 (9.7%) 0 (0.0%) 15 (13.6%) 0 (0.0%) 0 (0.0%)
Bilateral patchy shadowing 92 (59.4%) 0 (0.0%) 65 (59.1%) 22 (73.3%) 5 (33.3%)
consolidation 18 (11.6%) 0 (0.0%) 4 (3.6%) 6 (20.0%) 8 (53.3%)
Routine blood test
White-cell count, E+09/L 33.555 .000
 ≥10 19 (12.1%) 0 (0.0%) 4 (3.6%) 4 (13.3%) 11 (73.3%)
 ≥4, <10 125 (79.6%) 2 (100.0%) 93 (84.5%) 26 (86.7%) 4 (26.7%)
 <4 13 (8.3%) 0 (0.0%) 13 (11.8%) 0 (0.0%) 0 (0.0%)
Lymphocyte count, E+09/L 12.133 .000
 ≥4 2 (1.3%) 0 (0.0%) 1 (0.9%) 1 (3.3%) 0 (0.0%)
 ≥0.8, <4 97 (61.8%) 1 (50.0%) 78 (70.9%) 14 (46.7%) 4 (26.7%)
 <0.8 58 (36.9%) 1 (50.0%) 31 (28.2%) 15 (50.0%) 11 (73.3%)
Platelet count, E+09/L 0.191 .662
 ≥300 4 (2.5%) 0 (0.0%) 4 (3.6%) 0 (0.0%) 0 (0.0%)
 ≥100, <300 112 (71.3%) 1 (50.0%) 81 (73.6%) 21 (70.0%) 9 (60.0%)
<100 41 (26.1%) 1 (50.0%) 25 (22.7%) 9 (30.0%) 6 (40.0%)
Hematocrit 4.644 .031
 <40 (male), <35 (female) 98 (62.4%) 0 (0.0%) 64 (58.2%) 23 (76.7%) 11 (73.3%)
 40–50 (male), 35–45 (female) 59 (37.6%) 2 (100.0%) 46 (41.8%) 7 (23.3%) 4 (26.7%)
C-reactive protein (mg/L) 15.280 .000
 >8 111 (70.7%) 0 (0.0%) 70 (63.6%) 26 (86.7%) 15 (100.0%)
 ≤8 46 (29.3%) 2 (100.0%) 40 (36.4%) 4 (13.3%) 0 (0.0%)
D-dimer (mg/L) 26.665 .000
 >0.55 104 (66.2%) 0 (0.0%) 60 (54.5%) 29 (96.7%) 15 (100.0%)
 ≤0.55 53 (22.8%) 2 (100.0%) 50 (45.5%) 1 (3.3%) 0 (0.0%)