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. 2021 May 14;100(19):e25923. doi: 10.1097/MD.0000000000025923

Table 1.

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Comorbidities Other treatments ETI/NIV CRP (mg/dl) LDH (U/L) CPK (U/L) Ferritin (μg/L) D-Dimer (ng/mL) Outcome (x109/L) IL-6 (pg/mL) Limphocytes
a b c a b c a b c a b c a b c a b c
P1: W, 76y HTN, DMII, AF lopinavir/ritonavira ETI 68 153 18 293 309 247 46 44 27 302 442 348 774 124,9 0,37 0,90 1,35 Discharged home 22 days after sarilumab
hydroxychloroquine plus azithromycinb,∗∗
P2: W, 71y HTN, DMII hydroxychloroquine plus azithromycinb NIV 221 330 15 608 528 292 424 159 3771 2529 2272 2036 0,97 0,89 1,76 Discharged home 19 days after sarilumab
P3: M, 78y HTN, COPD, AF, Obesity hydroxychloroquine plus azithromycinb NIV 143 152 208 287 398 435 869 179 151 1198 3394 302 515 380 0,64 0,47 0,57 Death 2 days. after sarilumab
P4: W, 79y HTN, DLP CKDIIIa, hydroxychloroquine plus azithromycinb NIV 400 480 766 713 160 319 83275 31975 65,2 0,71 0,45 Death 6days after sarilumab
prednisolone 250 mgc
P5: M, 62y HTN, DMII, hepatic fibrosis hydroxychloroquine plus azithromycinb NIV 76 123 25 331 334 221 326 581 461 727 856 1546 98,7 1,29 1,72 1,98 FiO2(21%) 9 days after sarilumab

AF = atrial fibrillation, CKD = chronic kidney disease, COPD = chronic obstructive pulmonary disease, DLP = dyslipidemia, DM = diabetes mellitus, ETI = endotracheal intubation, HTN = hypertension, NIV = non invasive ventilation.

a

At admission.

b

Before sarilumab.

c

After sarilumab.

∗∗

Hydrochloroquine 400 mg/12h (1d) followed by 200 mg/12h (4 more days) plus azithromycin 500 mg/d (3 days).