FIGURE 6.

Pig AMI model perfusion. A, Pigs were sedated, occluded of their left anterior descending coronary artery, reperfused for 1 hour, and administered the designated bioreactor (acellular or cellular) for 12 hours of perfusion. B and C, Comparative measurements of induced stress were done through serum sampling of Troponin I levels at the 12 hour mark, as well as morphological analysis of % infarct area at sacrifice. D and E, Heparin was administered over the course of 12 hours to maintain an ACT of approximately 300 seconds. N = 4 pigs per group. Error bars represent ± SD