TABLE 5.
Baseline Demographics, Comorbidities and Clinical Severity Factors in Patients With Spontaneous IVH, Stratified by Timing of Initiation of VTE Prophylaxis
| Demographic factors | VTE prophylaxis ≤ 72 h (n = 162) | VTE prophylaxis > 72 h (n = 239) | P value |
|---|---|---|---|
| Mean age (SD), yr | 59.3 (11.5) | 58.3 (11.4) | .46 |
| Female gender | 76 (46.9) | 110 (46.0) | .86 |
| Glasgow coma scale at screeninga | 10 (7-14) | 10 (7-14) | .59 |
| NIHSS at screeninga | 17 (4-29) | 13 (4-24) | .004 |
| ICH location | |||
| Thalamus | 107 (66.0) | 126 (52.7) | .01 |
| Nonthalamic | 55 (34.0) | 113 (47.3) | |
| Stability IVH volumea | 20.0 (12.5-30.5) | 22.5 (12.7-39.9) | .07 |
| Stability ICH volumea | 8.5 (3.6-15.7) | 7.6 (2.6-14.3) | .14 |
| Intraventricular alteplase use | 81 (50.0) | 116 (48.5) | .84 |
| Withdrawal of active treatment | 17 (10.5) | 26 (10.9) | .90 |
| More than one EVD | 61 (37.7) | 89 (36.8) | .86 |
| Asymptomatic hemorrhage | 40 (24.7) | 48 (20.1) | .32 |
| Symptomatic hemorrhage | 4 (2.5) | 9 (3.8) | .57 |
| Catheter tract hemorrhage | 34 (21.0) | 43 (18.0) | .39 |
| First 100 patients | 16 (9.9) | 52 (21.8) | .002 |
| Remaining 400 patients | 146 (90.1) | 187 (78.2) | |
Abbreviations: EVD, External ventriculostomy drain; ICH: Intracerebral hemorrhage; IVH: Intraventricular hemorrhage; mL: milliliters; SD: Standard deviation; VTE, venous thromboembolism.
aindicates values represented as median (interquartile range). Bold font represents statistical significance.