Table 3. Plasma levels of VEGF, PlGF and sFlt1 between cases and controls.

Angiogenic factors	Controls Median (IQR)	Cases Median (IQR)	p-value
VEGF (pg/ml)	1.20 (0.64–1.91)	0.71 (0.38–1.11)	< 0.001
PlGF (pg/ml)	84.62 (34.00–154.45)	2.20 (1.08–5.86)	< 0.001
sFlt1 x 103 (pg/ml)	19.86 (14.20–29.37)	141.33 (71.76–227.10)	< 0.001
sFlt1/PlGF x 103	0.222 (0.101–0.104)	73.37 (16.46–184.80)	< 0.001

PlGF, placental growth factor; VEGF, vascular endothelial growth factor; sFlt1, soluble fms like tyrosine kinase; sFlt1/PlGF, soluble fms like tyrosine kinase/placental growth factor ratio.