Table 2.

Treatment response, colchicine side effects, genetic testing, and family history of patients with PFAPA syndrome.

Patients	Flares before colchicine (N)	Duration flares before colchicine (days)	Highest degree of fever before colchicine (ºC)	Flares after colchicine (N)	Duration flares after colchicine (days)	Highest degree of fever after colchicine (ºC)	Side effects of colchicine	Genetic testing	Genetic testing results	Family history
1	8	3.75	39.5	2	1	38.5	No	Yes	No mutation	No
2	7	4	40	2	1.25	39	No	Yes	MEFV p. I640M	No
3	6	5.25	39	2	1	38.5	No	No	Not available	No
4	7	6	39.8	3	1.5	38.9	No	Yes	MEFV p.I591T	No
5	12	3.75	39.3	12	3.25	39	Abdominal pain	Yes	No mutation	Mother with PFAPA-like
6	8	4.25	39.8	3	1	38.8	No	Yes	No mutation	No
7	4	2.25	40.5	4	2.5	39	Vomiting	Yes	No mutation	Both parents with PFAPA-like
8	8	3.5	40	4	1.5	38.6	Diarrhea	Yes	MEFV p.R202Q	No
9	15	3	39.5	4	1	37.5	No	Yes	TNFR61A pR121Q	Both parents with PFAPA-like
10	9	10	40	3	3	38	No	No	Not available	No
11	14	5	40	2	1	37.5	No	Yes	No mutation	Mother with PFAPA-like
12	14	3	40	11	1	38	No	No	Not available	No
13	14	4	40	4	1	37.5	No	No	Not available	No

N: number; ºC: degrees celsius; PFAPA: periodic fever, aphthous stomatitis, pharyngitis, and adenitis.