Wilson disease in an 11-year-old girl with abnormal findings on a liver function test.
A, Initial T1-weighted axial MR image shows a subtle increased signal intensity in both globus pallidi (arrows).
B, Follow-up T1-weighted axial MR image obtained after 5 years shows increased extent of the lesion (arrows). Patient’s Child-Pugh class was Child C, despite adequate penicillamine therapy, and she had intractable ascites and a bleeding tendency.