Table 2.

Absolute event rates of first recurrent ICH, ischaemic stroke, or any serious vascular event in patients with ICH stratified by ICH location and history of AF

		Recurrent ICH		Ischaemic stroke		Serious vascular event*
		Number of events/patient-years	Event rate per 100 patient-years (95% CI)	Number of events/patient-years	Event rate per 100 patient-years (95% CI)	Number of events/patient-years	Event rate per 100 patient-years (95% CI)
All
OXVASC (n=255)†		15/626	2·4 (1·3–4·0)	7/637	1·1 (0·4–2·3)	35/616	5·7 (4·0–7·9)
LATCH (n=419)		31/788	3·9 (2·7–5·6)	18/801	2·3 (1·3–3·6)	83/785	10·6 (8·4–13·1)
Pooled		46/1414	3·2 (2·0–5·1)	25/1438	1·7 (0·8–3·3)	118/1401	7·9 (4·3–14·4)
ICH location
OXVASC
	Lobar (n=109)	11/275	4·0 (2·7–7·2)	4/275	1·5 (0·4–3·7)	23/271	8·5 (5·4–12·7)
	Non-lobar (n=144)	4/351	1·1 (0·3–2·9)	3/362	0·8 (0·2–2·4)	12/345	3·5 (1·8–6·1)
LATCH
	Lobar (n=208)	22/384	5·7 (3·6–8·7)	8/388	2·1 (0·9–4·1)	42/384	10·9 (7·9–14·8)
	Non-lobar (n=211)	9/404	2·2 (1·0–4·2)	10/412	2·4 (1·2–4·5)	41/401	10·2 (7·3–13·9)
Pooled
	Lobar (n=317)	33/659	5·1 (3·6–7·2)	12/664	1·8 (1·0–3·2)	65/656	10·0 (7·8–12·8)
	Non-lobar (n=355)	13/755	1·8 (1·0–3·3)	13/774	1·6 (0·6–4·4)	53/745	6·1 (2·1–17·6)
Comorbid AF
OXVASC
	AF (n=57)	1/81	1·2 (0·0–6·9)	6/81	7·4 (2·7–16·1)	9/79	11·5 (5·2–21·8)
	No AF (n=198)	14/545	2·6 (1·4–4·3)	1/556	0·2 (0·0–1·0)	26/537	4·8 (3·2–7·1)
LATCH
	AF (n=90)	6/126	4·8 (1·8–10·4)	7/127	5·5 (2·2–11·4)	23/126	18·2 (11·6–27·4)
	No AF (n=328)	25/662	3·8 (2·4–5·6)	11/674	1·6 (0·8–2·9)	60/659	9·1 (7·0–11·7)
Pooled
	AF (n=147)	7/207	3·3 (1·0–10·7)	13/208	6·3 (3·7–10·9)	32/205	15·5 (10·0–24·1)
	No AF (n=526)	39/1207	3·2 (2·2–4·7)	12/1230	0·7 (0·1–5·6)	86/1196	6·8 (3·6–12·5)

AF=atrial fibrillation. ICH=intracerebral haemorrhage. LATCH=Lothian Audit of the Treatment of Cerebral Haemorrhage. OXVASC=Oxford Vascular Study.

^*Non-fatal stroke or myocardial infarction, or vascular death.

^†Cause of death data missing for three patients because patients moved out of the area or abroad.