Table 2:
Brain volume (milliliters) differences between values at week 0 and week 12, expressed in several ways*
| Structure | Absolute Difference |
Max Volume Change |
Max Percent Change |
|||
|---|---|---|---|---|---|---|
| Mean | SD | Decrease | Increase | Decrease | Increase | |
| Whole brain | 17.9 | 17.7 | −68.3 | 77.3 | −5.7 | 6.5 |
| L frontal GM | 3.3 | 3.6 | −6.7 | 19.8 | −4.3 | 12.6 |
| R frontal GM | 3.0 | 2.9 | −6.3 | 17.8 | −3.9 | 11.1 |
| L occipital GM | 1.6 | 1.4 | −5.2 | 7.4 | −8.8 | 12.5 |
| R occipital GM | 1.4 | 1.6 | −5.1 | 6.8 | −8.6 | 11.4 |
| L parietal GM | 1.6 | 1.2 | −5.9 | 4.8 | −9.4 | 7.7 |
| R parietal GM | 1.7 | 1.8 | −7.1 | 8.5 | −11.1 | 13.3 |
| L temporal GM | 2.2 | 2.1 | −6.0 | 9.4 | −8.9 | 13.9 |
| R temporal GM | 2.4 | 2.3 | −7.7 | 10.7 | −11.2 | 15.6 |
| L frontal WM | 3.8 | 3.7 | −9.7 | 21.3 | −6.8 | 15.0 |
| R frontal WM | 3.9 | 3.6 | −11.1 | 21.1 | −7.8 | 14.8 |
| L occipital WM | 1.0 | 1.0 | −3.4 | 3.6 | −19.9 | 21.1 |
| R occipital WM | 1.0 | 0.8 | −2.9 | 3.2 | −16.6 | 18.3 |
| L parietal WM | 1.3 | 1.2 | −7.1 | 3.6 | −15.4 | 7.8 |
| R parietal WM | 1.5 | 1.1 | −5.1 | 3.5 | −11.1 | 7.6 |
| L temporal WM | 1.5 | 1.5 | −6.5 | 5.7 | −18.1 | 15.8 |
| R temporal WM | 1.6 | 1.4 | −5.0 | 6.5 | −13.9 | 18.0 |
| L caudate | 0.4 | 0.3 | −1.2 | 2.1 | −27.9 | 48.8 |
| R caudate | 0.4 | 0.4 | −2.1 | 1.8 | −43.8 | 37.5 |
Note:—L, left; R, right; Max, maximum; GM, gray matter; WM, white matter.
*
The absolute difference is unaffected by the sign of the change from week 0 to week 12. The maximal decrease and increase from week 0 to week 12 is expressed as volume (with units of milliliters) and as percent change (with respect to baseline).