Table 2:
Conventional MRI detection of RNBS-positive skull metastasis
| Cancer Type | Sensitivity |
Specificity |
κ | Agreement Beyond Chance of 2 Readers | ||
|---|---|---|---|---|---|---|
| Reader 1 (%) | Reader 2 (%) | Reader 1 (%) | Reader 2 (%) | |||
| Overall, n = 75 | 55.3 (21/38) | 42.1 (16/38) | 97.3 (36/37) | 100 (37/37) | 0.65 (62/75) | Substantial |
| Lung, n = 32 | 27.3 (3/11) | 36.4 (4/11) | 100 (21/21) | 100 (21/21) | 0.81 (29/32) | Almost perfect |
| Breast, n = 20 | 80 (12/15) | 60 (9/15) | 100 (5/5) | 100 (5/5) | 0.50 (15/20) | Moderate |
| Prostate, n = 8 | 42.9 (3/7) | 14.3 (1/7) | 100 (1/1) | 100 (1/1) | 0 (4/8) | None |
| Other, n = 15 | 60 (3/5) | 40 (2/5) | 90 (9/10) | 100 (10/10) | 0.93 (13/15) | Almost perfect |
Note:—Other indicates genitourinary and gastrointestinal cancer, Ewing sarcoma, lymphoma, myxoid chondrosarcoma, squamous cell cancer of the head and neck, and thymic and undifferentiated cancer.