Table 1.
Durvalumab + EP (n = 18) | EP (n = 16) | All patients (n = 34) | |
---|---|---|---|
Median age (range), years | 67.5 (40–82) | 69.5 (46–82) | 69 (40–82) |
Age group, n (%) | |||
< 65 | 5 (28) | 5 (31) | 10 (29) |
≥ 65 | 13 (72) | 11 (69) | 24 (71) |
Sex, n (%) | |||
Men | 14 (78) | 14 (88) | 28 (82) |
Women | 4 (22) | 2 (13) | 6 (18) |
Median body weight (range), kg | 58.0 (50.0–93.0) | 60.0 (41.0–91.0) | 58.5 (41.0–93.0) |
Disease stage, n (%) | |||
IIIB | 3 (17) | 1 (6) | 4 (12) |
IV | 15 (83) | 15 (94) | 30 (88) |
WHO performance status, n (%) | |||
0 | 7 (39) | 4 (25) | 11 (32) |
1 | 11 (61) | 12 (75) | 23 (68) |
Smoking history, n (%) | |||
Never smoker | 0 | 0 | 0 |
Former smoker | 17 (94) | 14 (88) | 31 (91) |
Current smoker | 1 (6) | 2 (13) | 3 (9) |
Brain or CNS metastases, n (%) | 1 (6) | 3 (19) | 4 (12) |
Liver metastases, n (%) | 10 (56) | 7 (44) | 17 (50) |
CNS central nervous system, EP platinum-etoposide, WHO World Health Organization