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. 2021 May 19;11:10565. doi: 10.1038/s41598-021-89943-5

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© The Author(s) 2021, corrected publication 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The efficiency of the siRNA transfer in vitro with the engineered fullerene nanomaterials HexakisaminoC₆₀ and JK39 and the resulting EGFP silencing in a prostate cancer model (DU145 cells that had been transfected with the plasmid encoding EGFP). Each value represents the mean ± SD (n = 3). Statistical significance was determined using the t-test (*p < 0.05; **p < 0.01; ***p < 0.001).