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. 2021 May 19;11:296. doi: 10.1038/s41398-021-01412-9

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — The figures show the regional association plot of known representative loci, (A) 11q14.2; PICALM and (B) 19q13.32; APOE, in the cAD chip application set (n = 1,437). The purple shaded diamond shape represents rs3851179 and rs429358, which are the most significant SNPs in 11q14.2 (A) and 19q13.32 (B), respectively. The blue line indicates the recombination rate, while filled color represents the linkage disequilibrium score based on r² values estimated from the 1000 genome Nov 2014 ASN data.