Table 2.

Disorder-specific heritability attributable to common variants, SNP heritability of disorders partitioned across sQTLs and eQTLs^a.

Diagnosis	Schizophrenia	Bipolar disorder	Major depression	Alzheimer’s disease
N SNPs	10,69,224	9,62,367	10,60,414	10,35,603
Observed h2 (se)	0.4 (0.015)	0.3 (0.018)	0.05 (0.003)	0.046 (0.009)
Proportion sQTLs	0.04	0.04	0.04	0.04
Observed sQTL h2 (se)	0.08 (0.01)	0.07 (0.01)	0.05 (0.01)	0.06 (0.04)
sQTL enrichment (se)	2.1 (0.26)	1.7 (0.31)	1.2 (0.26)	1.5 (0.90)
sQTL enrichment p	3.3E−05	0.02	0.38	0.55
Bonferroni p	9.8E−05	0.06	1	1
Proportion eQTLs	0.06	0.06	0.06	0.06
eQTL h2 (se)	0.11 (0.01)	0.08 (0.01)	0.05 (0.01)	0.12 (0.04)
eQTL enrichment (se)	1.7 (0.18)	1.3 (0.22)	0.8 (0.17)	2.0 (0.71)
eQTL enrichment p	9.00E−05	0.13	0.41	0.14
Proportion eQTLs not sQTLS	0.02	0.02	0.02	0.02
eQTL h2 (se)	0.03 (0.007)	0.02 (0.009)	0.01 (0.008)	0.08 (0.032)
eQTL enrichment (se)	1.16 (0.27)	0.81 (0.38)	0.48 (0.31)	3.33 (1.3)
eQTL enrichment p	0.54	0.62	0.10	0.05

^aExcludes eQTLs that are also sQTLs.